Antiemetic Medication Choices Based on Clinical Scenarios

ConditionFirst-Line AntiemeticConsiderations/Contraindications
Renal Failure / Hypercalcemia / Toxin Induced VomitingHaloperidolContraindicated in Parkinson’s disease.
Levomepromazine or Cyclizine are alternatives
Increased Intracranial Pressure (ICP) or Bowel ObstructionCyclizineSuitable for ICP or bowel obstruction scenarios
Delayed Gastric Emptying (e.g., Peritoneal Metastasis)MetoclopramideProkinetic, do not use with Parkinson’s disease
Chemotherapy or Radiotherapy Induced VomitingOndansetronEffective for chemo or radiotherapy-induced nausea and vomiting

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