Monitoring and Adverse Effects of Amiodarone:

Regular Monitoring:

• Liver Function Tests (LFT)
• Thyroid Function Tests (TFT)
• Chest X-ray (CXR)
• Electrocardiogram (ECG)

Frequency:

• TFT and LFT: Every 6 months
• ECG: Every 12 months

Adverse Effects:

• Pulmonary fibrosis (most serious) and pneumonitis
• Thyroid dysfunction: Both hypothyroidism and hyperthyroidism
• Liver fibrosis/hepatitis
• Corneal deposits
• Peripheral neuropathy and myopathy
• Photosensitivity
• Slate-grey skin discoloration
• Bradycardia
• Prolonged QT interval
• Thrombophlebitis and injection site reactions (usually given via central veins)