Kawasaki Disease

Signs and Symptoms:

1. High-grade fever lasting more than 5 days.
2. Bilateral non-exudative conjunctivitis.
3. Bright red cracked lips.
4. “Strawberry” tongue.
5. Painless cervical lymphadenopathy.
6. Red palms and soles, which later peel (desquamation).
7. Polymorphous rash.

Initial Investigation:

i. Clinical diagnosis: Based on history and physical examination.
ii. Echocardiogram: To screen for coronary artery aneurysms.

Management:

. High-dose aspirin: To reduce inflammation and prevent clot formation.
. Intravenous immunoglobulin (IVIG): To reduce the risk of coronary artery aneurysms and shorten the duration of fever.
. Low-dose aspirin: Continued after the acute phase to prevent coronary artery thrombosis.

Complications:
. Coronary artery aneurysms.
. Myocarditis.
. Arrhythmias.